THE EFFECTIVENESS OF THERAPY FOR PARVOVIRUS ENTERITIS IN DOGS USING IMMUNOPHAN AND GAMAVIT DRUGS

Authors

DOI:

https://doi.org/10.71453/

Keywords:

parvovirus enteritis, parvoviruses, PVS-1, PVS-2, canine, immunoglobulin, therapeutic efficacy

Abstract

The treatment of canine parvovirus enteritis continues to be a significant problem in modern veterinary medicine. The urgency of solving the problem is due to the need to find an effective treatment for this disease. The article presents the results of a study on the therapeutic effectiveness of various treatment regimens for parvovirus enteritis: scheme 1 (experimental group) - symptomatic therapy + immunophan and gamavit drugs and the 2nd treatment regimen (control group) – symptomatic therapy + Giskan-5 drug. The experiment was conducted on the basis of the Central Veterinary Hospital in Kiselevsk. For the experiment, 12 puppies aged 2.5 months with clinical signs of the disease (vomiting, diarrhea with a characteristic odor) were selected. The diagnosis was confirmed by the results of a diagnostic test and hematological examinations. At the initial admission of the animals and on the 10th day after the start of treatment, blood samples were taken from both groups of animals to assess the overall blood count. On the 5th day of treatment, an improvement in the general condition was observed in the experimental group of animals: absence of fever, vomiting and diarrhea. At the beginning of the experiment, both groups had a reduced ESR content (from 3.3±0.6 to 3.5±0.5 mm/h), which indicates circulatory disorders or cardiovascular diseases. A low white blood cell count at the beginning of the experiment (from 3.4± 3.1 to 4.1±1.7×109/l) indicates the presence of a viral infection. On the 10th day of treatment, the ESR values increased (from 4.2±0.1 to 5.3±0.2 mm/h), the white blood cell level was within the normal range (from 11.1±1.3 to 13.4± 1.1×109/l). The physiological condition of the animals (temperature, pulse, respiration, mucosal staining) was satisfactory.

Based on clinical signs and morphophysiological parameters, on the 10th day after the start of treatment, the high therapeutic efficacy of the proposed regimen (symptomatic therapy + Immunophane and Gamavit preparations) was confirmed.

Author Biographies

  • Sergej Yu. Grachev, Kuzbass State Agrarian University

    Candidate of Agricultural Sciences

  • Tatyana V. Zubova , Kuzbass State Agrarian University

    Doctor of Biological Sciences, head of the department of veterinary medicine end biotechnology

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Published

2026-02-10

Issue

№ 4(8) 2025

Section

ПРОДУКТИВНОЕ ЖИВОТНОВОДСТВО

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